Product Specifications Anti-HCV Helicase. IgG fraction (monoclonal):

Description:IgG fraction from mouse monoclonal antibody (clone 5F6/H11) obtained by immunization of mice with Helicase antigen (50 kDa) from aa1193 - aa1657 of HCV 1a polyprotein. The IgG fraction was purified using Protein G-Sepharose.

Isotype: IgG1

Storage: Store at -20 °C.

Stability: Stable for at least one year. Avoid repeated freezing and thawing.

Biological Activity:  This antibody can be used in ELISA assays (1:100,000 dilution) and Western Blot analysis (1:16,000 dilution). HCV Helicase is a nucleotide triphosphate - dependent enzyme that catalyzes the unwinding of positive - stranded RNA from hepatitis C virus.

Formulation: Solution at 1.0 mg/mL in PBS.

References:     

Yao, N. et al (1997) Nat. Struct. Biol. 4, 463 - 467.
Grakoui, A. et. al. (1993) J. of Virol. 65, 2832 - 2843.
Choo,Q.-L. et. al. (1991) Proc. Natl. Acad. Sci. USA 88, 2451-
2455.

 Datasheet for Anti-Hepatitis C Virus Helicase, monoclonal, mouse